Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354290 | 0.82 | MAPT (0.60) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL56902 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL29397257 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4EMEN1LMNA | |
| Ammonia Solution, Strong SCHEMBL28913421 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4EMEN1LMNA | |
| Charcoal, Activated SCHEMBL31112505 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL1072303 | 0.80 | S100B (0.55) | MAPTALDH1A1KDM4EMEN1LMNA | |
| Acrylic Acid SCHEMBL28390613 | 0.80 | MAPT (0.52) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL23498169 | 0.79 | MAPT (0.70) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL8409320 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL2316177 | 0.78 | MAPT (0.69) | MAPTALDH1A1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150586-B1 | DYES HAVING RATIOMETRIC FLUORESCENCE RESPONSE FOR DETECTING METABOLITES | BECTON DICKINSON CO (US) | 2018-03-14 | — | — | EP | disclosed |