Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.56 |
| ▸ | TET3 | O43151 | 1/20 | 0.56 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001779 | 1.00 | TET2 (0.56) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL1995657 | 1.00 | TET2 (0.56) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL2966907 | 0.79 | — | — | |
| SCHEMBL11037132 | 0.76 | TET2 (0.64) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL6064308 | 0.75 | TET2 (0.50) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL6063635 | 0.73 | TET2 (0.48) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL10710528 | 0.73 | — | — | |
| SCHEMBL18334352 | 0.73 | — | — | |
| SCHEMBL1993690 | 0.72 | TET2 (1.00) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL1993688 | 0.72 | TET2 (1.00) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513121-A1 | PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | Piramal Imaging SA (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2012104225-A1 | DERIVATIZATION OF RADIOPHARMACEUTICALS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-08-09 | — | — | WO | disclosed |
| EP-2338892-A1 | Prostate specific membrane antigen inhibitors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-06-29 | — | — | EP | disclosed |
| WO-2011073286-A1 | PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-23 | — | — | WO | disclosed |