SCHEMBL6064308

SCHEMBL6064308

C=C(CC(F)C(F)F)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.50
TET3 O43151 1/20 0.50
TET1 Q8NFU7 1/20 0.50
GRIK1 P39086 1/20 0.48
GRIK2 Q13002 1/20 0.48
GRM1 Q13255 1/20 0.48
GRM2 Q14416 1/20 0.48
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064272 0.86 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL6063735 0.81 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL2966907 0.79
SCHEMBL2001779 0.75 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL1995657 0.75 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL1995655 0.75 TET2 (0.56) TET2TET3TET1GRIK1GRIK2
SCHEMBL6063635 0.73 TET2 (0.48) TET2TET3TET1GRIK1GRIK2
SCHEMBL1171695 0.73
SCHEMBL11037132 0.70 TET2 (0.64) TET2TET3TET1GRIK1GRIK2
SCHEMBL2158348 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148363-B2 Process for preparing acrylate compound TOSOH CORPORATION (JP) 2006-12-12 US disclosed
US-20050148789-A1 Process for preparing acrylate compound TOSOH CORPORATION 2005-07-07 US disclosed
US-6833462-B2 Esterification to get cyclic acrylate compounds; used as raw material for functional polymers, pharmaceuticals, pesticides, semiconductor lithography TOSOH CORPORATION (JP) 2004-12-21 US disclosed
US-20030139613-A1 Process for preparing acrylate compound TOSOH CORPORATION 2003-07-24 US disclosed
US-5612281-A Recording sheet FUJI PHOTO FILM CO., LTD. (JP) 1997-03-18 US disclosed
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed
US-5235013-A Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester CIBA-GEIGY CORPORATION 1993-08-10 US disclosed
EP-0478261-A2 Process for producing oxygen-permeable polymer CIBA-GEIGY AG (CH) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139613-A1 Process for preparing acrylate compound AFF1, AFF4, RER1 TET2 1456/4885TET3 2642/4885TET1 2849/4885
US-20050148789-A1 Process for preparing acrylate compound ACR, AFF4, AFF1 TET2 1202/4885TET3 2886/4885TET1 3338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.