Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517281 | 0.89 | KMT2A (0.53) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL8178904 | 0.74 | MEN1 (0.60) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL3765025 | 0.69 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4088776 | 0.68 | TSHR (0.50) | NPC1RAB9ASMN1; SMN2MAPK1HPGD | |
| SCHEMBL517372 | 0.67 | HPGD (0.56) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL1429353 | 0.66 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1852594 | 0.66 | PRKCI (0.41) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL31553362 | 0.66 | MPO (0.50) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL517510 | 0.66 | HPGD (0.59) | KMT2AMEN1MAPTMAPK1HPGD | |
| SCHEMBL6132176 | 0.65 | MEN1 (0.63) | NPC1RAB9ASMN1; SMN2KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392458-B1 | POLYPROPYLENE RESIN MOLDED ARTICLE | NEW JAPAN CHEM CO LTD (JP) | 2018-03-14 | — | — | EP | disclosed |