SCHEMBL517372

SCHEMBL517372

O=C(c1ccc(C2OCC3(CO2)COC(c2ccc(C(=O)N4CCCC4)cc2)OC3)cc1)N1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.56
ALDH1A1 P00352 4/20 0.56
MAOA P21397 1/20 0.52
MAPK1 P28482 1/20 0.47
L3MBTL3 Q96JM7 6/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
MBTD1 Q05BQ5 4/20 0.46
MLYCD O95822 1/20 0.46
TP53BP1 Q12888 1/20 0.46
L3MBTL4 Q8NA19 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517510 0.98 HPGD (0.59) HPGDALDH1A1MAOAMAPK1L3MBTL3
SCHEMBL9946167 0.78 HPGD (0.59) HPGDALDH1A1MAOAMAPK1L3MBTL3
SCHEMBL8178904 0.77 MEN1 (0.60) HPGDALDH1A1MAPK1MEN1KMT2A
SCHEMBL10721733 0.76 HPGD (0.95) HPGDALDH1A1MAPK1L3MBTL3L3MBTL1
SCHEMBL517281 0.76 KMT2A (0.53) HPGDALDH1A1MAPK1L3MBTL1MEN1
SCHEMBL27479149 0.74 HPGD (1.00) HPGDALDH1A1MAOAMAPK1L3MBTL3
SCHEMBL7132525 0.74 HPGD (1.00) HPGDALDH1A1MAOAMAPK1L3MBTL3
SCHEMBL19217285 0.71 HPGD (0.69) HPGDALDH1A1MAOAL3MBTL3L3MBTL1
SCHEMBL517308 0.70 LMNA (0.54) MEN1KMT2ACYP2C19GAANPC1
SCHEMBL6132176 0.69 MEN1 (0.63) ALDH1A1MAPK1MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
EP-2431415-A1 METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN New Japan Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-09 US disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN MNAT1, RFT1, RTF1 HPGD 2525/4885ALDH1A1 2124/4885MAOA 985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.