Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097219 | 1.00 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL1531697 | 1.00 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL1995664 | 1.00 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL1532151 | 1.00 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL16817867 | 0.83 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL16817902 | 0.83 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL16817909 | 0.83 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL2244738 | 0.83 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL1468681 | 0.82 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 | |
| SCHEMBL1468682 | 0.82 | SLC6A1 (0.33) | SLC6A1SLC6A11SLC6A13GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338888-A1 | Imidazopyridine derivatives as JAK inhibitors | Almirall, S.A. (ES) | 2011-06-29 | — | — | EP | disclosed |