Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19957718 | 0.87 | PRMT5 (0.73) | PRMT5WDR77 | |
| SCHEMBL19957640 | 0.86 | PRMT5 (0.71) | PRMT5WDR77 | |
| SCHEMBL16417642 | 0.85 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL16417571 | 0.85 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL16417650 | 0.85 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL19957605 | 0.80 | PRMT5 (0.72) | PRMT5WDR77 | |
| SCHEMBL19957637 | 0.79 | PRMT5 (0.71) | PRMT5WDR77 | |
| SCHEMBL15818387 | 0.79 | PRMT5 (0.69) | PRMT5WDR77 | |
| SCHEMBL19957616 | 0.79 | PRMT5 (0.51) | PRMT5WDR77 | |
| SCHEMBL19957594 | 0.77 | PRMT5 (0.71) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935243-B1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | EPIZYME INC (US) | 2018-03-14 | — | — | EP | disclosed |