SCHEMBL1995800

SCHEMBL1995800

O=[N+]([O-])c1c(C(F)(F)F)cccc1C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 2/20 0.46
EPAS1 Q99814 2/20 0.44
ABCC8 Q09428 3/20 0.41
KCNJ11 Q14654 3/20 0.41
TSHR P16473 2/20 0.41
GPR35 Q9HC97 2/20 0.41
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.38
KIF11 P52732 1/20 0.38
VEGFA P15692 1/20 0.37
FBP1 P09467 1/20 0.37
S100A4 P26447 1/20 0.36
RORC P51449 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459395 0.88 TSHR (0.53) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL972079 0.88 ALDH1A1 (0.41) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL29745147 0.86 EPAS1 (0.40) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL31285851 0.86 EPAS1 (0.46) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL27986034 0.86 EPAS1 (0.40) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL3520821 0.86 ALDH1A1 (0.64) TDP1ALDH1A1EPAS1TSHRCYP3A4
SCHEMBL504875 0.86 EPAS1 (0.40) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL6429 0.86 EPAS1 (0.46) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL2792217 0.86 GPR35 (0.56) TDP1ALDH1A1EPAS1ABCC8KCNJ11
SCHEMBL9096553 0.86 EPAS1 (0.40) TDP1ALDH1A1EPAS1ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed