Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367901 | 0.88 | HDAC1 (0.53) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL454516 | 0.88 | HDAC1 (0.53) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL420028 | 0.84 | HDAC1 (0.50) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL20897346 | 0.84 | HDAC1 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL14443343 | 0.83 | HDAC1 (0.57) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL19582860 | 0.82 | HDAC1 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL3210526 | 0.80 | HDAC1 (0.61) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL1684002 | 0.78 | HDAC1 (0.52) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL23265005 | 0.78 | PLOD2 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL31686043 | 0.78 | PLOD2 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180070627-A1 | Improvements in methods of treating tobacco | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2018-03-15 | — | — | US | disclosed |