Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367901 | 1.00 | HDAC1 (0.53) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL420028 | 0.96 | HDAC1 (0.50) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL20897346 | 0.96 | HDAC1 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL19958136 | 0.88 | HDAC1 (0.52) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL14443343 | 0.84 | HDAC1 (0.57) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL5484016 | 0.83 | HDAC1 (0.42) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL19582860 | 0.83 | HDAC1 (0.56) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL18106043 | 0.82 | HDAC1 (0.52) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL3210526 | 0.81 | HDAC1 (0.61) | HDAC1HDAC8PLOD2KMT2APLOD3 | |
| SCHEMBL3933153 | 0.80 | HDAC1 (0.50) | HDAC1HDAC8PLOD2KMT2APLOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638424-B2 | Method for determining tobacco-specific nitrosamines (TSNAs) in cigarette smoke using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) | YUNNAN ACADEMY OF TOBACCO AGRICULTURAL SCIENCES (CN) | 2026-05-26 | — | — | US | claimed |
| US-12628862-B2 | Liquid tobacco extract, method for making and aerosol-generating articles comprising such | PHILIP MORRIS PRODUCTS S.A. (CH) | 2026-05-19 | — | — | US | claimed |
| EP-2935588-B1 | TOBACCO SPECIFIC NITROSAMINE REDUCTION IN PLANTS | PHILIP MORRIS PRODUCTS SA (CH) | 2026-03-25 | — | — | EP | claimed |
| US-20260026543-A1 | TOBACCO FLAVOURED DRY POWDER FORMULATION | PHILIP MORRIS PRODUCTS SA (CH) | 2026-01-29 | — | — | US | claimed |
| EP-4684652-A1 | AEROSOL GENERATING MATERIAL | Nicoventures Trading Limited (GB) | 2026-01-28 | — | — | EP | claimed |
| US-20250388918-A1 | TOBACCO HAVING ALTERED LEAF PROPERTIES AND METHODS OF MAKING AND USING | ALTRIA CLIENT SERVICES LLC (US) | 2025-12-25 | — | — | US | claimed |
| EP-4311440-B1 | FIBROUS FILTRATION MATERIAL FOR ELECTRONIC SMOKING ARTICLE | RAI STRATEGIC HOLDINGS INC (US) | 2025-07-02 | — | — | EP | claimed |
| US-12195738-B2 | Method for modifying alkaloid content in plants | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2025-01-14 | — | — | US | claimed |
| US-20250011803-A1 | Composition and Methods for Producing Tobacco Plants and Products Having Reduced Tobacco-Specific Nitrosamines (TSNAs) | ALTRIA CLIENT SERVICES LLC (US) | 2025-01-09 | — | — | US | claimed |
| US-12129474-B2 | Composition and methods for producing tobacco plants and products having reduced tobacco-specific nitrosamines (TSNAs) | ALTRIA CLIENT SERVICES LLC (US) | 2024-10-29 | — | — | US | claimed |
| WO-2002037990-A2 | METHOD AND PRODUCT FOR REMOVING CARCINOGENS FROM TOBACCO SMOKE | VECTOR TOBACCO LTD. (BM) | 2002-05-16 | — | — | WO | claimed |
| WO-2002028209-A1 | REDUCTION OF NITROSAMINES IN TOBACCO AND TOBACCO PRODUCTS | BASKEVITCH NICOLAS (US) | 2002-04-11 | — | — | WO | claimed |
| US-6338348-B1 | PREVENTING FORMATION OF OF 4-(N-NITROSOMETHYLAMINO) 1-(3-PYRIDYL-1-BUTANONE ON TOBACCO LEAVES | REGENT COURT TECHNOLOGIES | 2002-01-15 | — | — | US | claimed |
| US-6311695-B1 | Method of treating tobacco to reduce nitrosamine content, and products produced thereby | REGENT COURT TECHNOLOGIES | 2001-11-06 | — | — | US | claimed |
| US-6135121-A | CURED YELLOW TOBACCO FREE OF ORGANIC LIQUIDS FOR EXTRACTION OF EXPANDED ORGANIC MATERIALS AND HAVING A COLLECTIVE CONTENT OF N'-NITROSO-NORNICOTINE, 4-(N-NITROSOMETHYLAMINO)-1-(3-PYRIDYL)-1-BUTANONE, | REGENT COURT TECHNOLOGIES (US) | 2000-10-24 | — | — | US | claimed |
| EP-0967898-A4 | METHOD OF TREATING TOBACCO TO REDUCE NITROSAMINE CONTENT, AND PRODUCTS PRODUCED THEREBY | WILLIAMS JONNIE R (US) | 2000-01-05 | — | — | EP | claimed |
| EP-0967898-A1 | METHOD OF TREATING TOBACCO TO REDUCE NITROSAMINE CONTENT, AND PRODUCTS PRODUCED THEREBY | Williams, Jonnie R. (US) | 2000-01-05 | — | — | EP | claimed |
| US-5803081-A | Tobacco and related products | REGENT COURT TECHNOLOGIES (US) | 1998-09-08 | — | — | US | claimed |
| WO-1998005226-A9 | METHOD OF TREATING TOBACCO TO REDUCE NITROSAMINE CONTENT, AND PRODUCTS PRODUCED THEREBY | — | 1998-07-02 | — | — | WO | claimed |
| WO-1998005226-A1 | METHOD OF TREATING TOBACCO TO REDUCE NITROSAMINE CONTENT, AND PRODUCTS PRODUCED THEREBY | WILLIAMS JONNIE R (US) | 1998-02-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12628862-B2 | Liquid tobacco extract, method for making and aerosol-generating articles comprising such | NDUFB10, EXOSC10, NDUFB7 | HDAC1 2421/4885HDAC8 2136/4885PLOD2 3122/4885 |
| US-20260026543-A1 | TOBACCO FLAVOURED DRY POWDER FORMULATION | CTNND1, IL17A, TAS2R20 | HDAC1 2881/4885HDAC8 3436/4885PLOD2 2869/4885 |
| US-12638424-B2 | Method for determining tobacco-specific nitrosamines (TSNAs) in cigarette smoke using one-step clean-up coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) | TYMS, NNMT, SRMS | HDAC1 3468/4885HDAC8 1995/4885PLOD2 1630/4885 |
| US-20250388918-A1 | TOBACCO HAVING ALTERED LEAF PROPERTIES AND METHODS OF MAKING AND USING | PRPF40A, UPF1, SLIRP | HDAC1 4348/4885HDAC8 3175/4885PLOD2 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.