Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307398 | 0.79 | HTR2A (0.36) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL1825426 | 0.79 | HTR2A (0.36) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL13797853 | 0.78 | HTR2A (0.33) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL7927923 | 0.78 | HTR2A (0.35) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL8191823 | 0.78 | HTR2A (0.35) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL31530501 | 0.78 | HTR2A (0.35) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL4652449 | 0.75 | HTR2A (0.39) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL1028330 | 0.75 | HTR2A (0.39) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL6674266 | 0.75 | HTR2A (0.33) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL20972410 | 0.75 | HTR2A (0.33) | HTR6HTR2ASIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180072822-A1 | METALLOCENE COMPOUND | LG CHEM, LTD. (KR) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | PCBP1, SOD1, PCLAF | HTR6 4077/4885HTR2A 4383/4885SIGMAR1 3378/4885 |
| US-20180072822-A1 | METALLOCENE COMPOUND | SOD1, PCNA, OR10J3 | HTR6 3845/4885HTR2A 3282/4885SIGMAR1 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.