Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.59 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960728 | 0.94 | CASP2 (0.69) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL19960886 | 0.92 | CASP2 (0.71) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL19960974 | 0.92 | CASP2 (0.71) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL1630120 | 0.91 | FAAH (0.73) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL25350370 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL2089790 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL11170358 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL227920 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL14576744 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 | |
| SCHEMBL846255 | 0.89 | FAAH (0.77) | FAAHDNM1CASP2NAAAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |