Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 6/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455984 | 0.97 | FAAH (0.60) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL28881094 | 0.97 | FAAH (0.60) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL8640203 | 0.92 | FAAH (0.59) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL6399330 | 0.92 | FAAH (0.59) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29302109 | 0.88 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL29300290 | 0.88 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23775006 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL11175734 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21633848 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22271678 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |