Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.85 |
| ▸ | ACHE | P22303 | 2/20 | 0.85 |
| ▸ | ODC1 | P11926 | 2/20 | 0.85 |
| ▸ | BCHE | P06276 | 1/20 | 0.85 |
| ▸ | BACE1 | P56817 | 1/20 | 0.85 |
| ▸ | HIF1AN | Q9NWT6 | 11/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960679 | 0.92 | PTPN1 (1.00) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL31376263 | 0.92 | PTPN1 (1.00) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL31376191 | 0.90 | PTPN1 (0.83) | PTPN1ACHEODC1BCHEBACE1 | |
| Lonchocarpin SCHEMBL29435870 | 0.89 | PTPN1 (0.83) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL13534952 | 0.88 | ACHE (1.00) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL31376270 | 0.88 | ACHE (1.00) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL16865502 | 0.83 | ODC1 (0.84) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL16694388 | 0.83 | HIF1AN (0.87) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL31376176 | 0.83 | HIF1AN (0.87) | PTPN1ACHEODC1BCHEBACE1 | |
| SCHEMBL16694389 | 0.83 | HIF1AN (0.87) | PTPN1ACHEODC1BCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | RAB35, GANC, GALE | PTPN1 4504/4885ACHE 66/4885ODC1 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.