SCHEMBL1996233

SCHEMBL1996233

CCCCC(=O)Oc1cc(F)cc(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
RECQL P46063 1/20 0.47
ALOX15 P16050 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
HTR7 P34969 1/20 0.39
POLM Q9NP87 1/20 0.37
POLK Q9UBT6 1/20 0.37
POLL Q9UGP5 1/20 0.37
POLH Q9Y253 1/20 0.37
TOP2A P11388 2/20 0.37
FAAH O00519 2/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
CTSB P07858 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996200 0.90 ALOX15 (0.44) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL27505452 0.86 KMT2A (0.48) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL2001585 0.83 ALOX15 (0.41) KMT2AKDM4ERECQLALOX15SMN1; SMN2
SCHEMBL29009858 0.82 KMT2A (0.43) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1994828 0.81 KMT2A (0.54) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1997560 0.81 KMT2A (0.54) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1998098 0.80 KMT2A (0.44) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL15763921 0.80 CES2 (0.44) CES2CES1CTSB
SCHEMBL15550319 0.79 ALOX15 (0.57) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1997102 0.79 KMT2A (0.43) KMT2AKDM4EMEN1RECQLALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed