Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | IGF2R | P11717 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | GJB2 | P29033 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19961998 | 0.99 | TLR4 (0.48) | TLR4IGF2RKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24797190 | 0.95 | TLR4 (0.54) | TLR4IGF2RPRKD3PRKCGPRKCB | |
| SCHEMBL19962099 | 0.95 | TLR4 (0.54) | TLR4IGF2RPRKD3PRKCGPRKCB | |
| SCHEMBL19958464 | 0.95 | TLR4 (0.54) | TLR4IGF2RPRKD3PRKCGPRKCB | |
| SCHEMBL12837376 | 0.86 | TLR4 (0.63) | TLR4GJB2 | |
| SCHEMBL13449598 | 0.86 | TLR4 (0.63) | TLR4GJB2 | |
| SCHEMBL19958459 | 0.86 | TLR4 (0.63) | TLR4GJB2 | |
| SCHEMBL19958448 | 0.84 | TLR4 (0.47) | TLR4KDM4EPOLBSMN1; SMN2PRKD3 | |
| SCHEMBL13875763 | 0.84 | TLR4 (0.47) | TLR4KDM4EPOLBSMN1; SMN2PRKD3 | |
| SCHEMBL19961853 | 0.84 | TLR4 (0.47) | TLR4KDM4EPOLBSMN1; SMN2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | CENTRAL MICHIGAN UNIVERSITY | 2023-05-04 | — | — | US | disclosed |
| US-11535642-B2 | Trehalose analogues | CENTRAL MICHIGAN UNIVERSITY (US) | 2022-12-27 | — | — | US | disclosed |
| US-10759821-B2 | Trehalose analogues | CENTRAL MICHIGAN UNIVERSITY (US) | 2020-09-01 | — | — | US | disclosed |
| US-20180072767-A1 | TREHALOSE ANALOGUES | NATIONAL SCIENCE FOUNDATION | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133705-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885IGF2R 657/4885KDM4E 4535/4885 |
| US-20180072767-A1 | TREHALOSE ANALOGUES | TREH, TALDO1, GALE | TLR4 2106/4885IGF2R 657/4885KDM4E 4535/4885 |
| US-10759821-B2 | Trehalose analogues | TREH, TALDO1, GALE | TLR4 2106/4885IGF2R 657/4885KDM4E 4535/4885 |
| US-11535642-B2 | Trehalose analogues | TREH, TALDO1, GALE | TLR4 2106/4885IGF2R 657/4885KDM4E 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.