SCHEMBL1996255

SCHEMBL1996255

Nc1ccc(CC2CN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CCN2CC(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.45
CHIT1 Q13231 2/20 0.38
DPP4 P27487 2/20 0.38
S1PR1 P21453 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA4 P22748 4/20 0.35
CA9 Q16790 4/20 0.35
SLC6A9 P48067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5864632 1.00 FOLH1 (0.45) FOLH1CHIT1DPP4S1PR1DPP7
SCHEMBL1079200 1.00 FOLH1 (0.45) FOLH1CHIT1DPP4S1PR1DPP7
SCHEMBL15904929 1.00 FOLH1 (0.45) FOLH1CHIT1DPP4S1PR1DPP7
SCHEMBL17119211 1.00 FOLH1 (0.45) FOLH1CHIT1DPP4S1PR1DPP7
Hydrochloric Acid SCHEMBL31226505 0.99 FOLH1 (0.44) FOLH1CHIT1DPP4S1PR1DPP7
SCHEMBL436094 0.94 LMNA (0.45) FOLH1CHIT1DPP4S1PR1CA1
SCHEMBL23627788 0.93 HSD17B10 (0.44) FOLH1CHIT1DPP4
SCHEMBL12974377 0.93 FOLH1 (0.41) FOLH1CHIT1DPP4SIGMAR1
SCHEMBL4098689 0.93 HSD17B10 (0.44) FOLH1CHIT1DPP4
SCHEMBL12261650 0.93 FOLH1 (0.41) FOLH1CHIT1DPP4S1PR1SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10806808-B2 Systems and methods for determining optimum patient-specific antibody dose for tumor targeting MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2020-10-20 US claimed
EP-3297669-B1 SYSTEMS AND METHODS FOR DETERMINING OPTIMUM PATIENT-SPECIFIC ANTIBODY DOSE FOR TUMOR TARGETING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2020-05-06 EP claimed
US-20180133350-A1 SYSTEMS AND METHODS FOR DETERMINING OPTIMUM PATIENT-SPECIFIC ANTIBODY DOSE FOR TUMOR TARGETING MEMORIAL SLOAN KETTERING CANCER CENTER 2018-05-17 US claimed
EP-3297669-A1 SYSTEMS AND METHODS FOR DETERMINING OPTIMUM PATIENT-SPECIFIC ANTIBODY DOSE FOR TUMOR TARGETING Memorial Sloan-Kettering Cancer Center (US) 2018-03-28 EP claimed
WO-2016191186-A1 SYSTEMS AND METHODS FOR DETERMINING OPTIMUM PATIENT-SPECIFIC ANTIBODY DOSE FOR TUMOR TARGETING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2016-12-01 WO claimed
US-6911457-B2 Imaging probes and methods for using the probes in diagnostic imaging processes and other imaging processes to determine physiological functions. CARBOMER, INC. (US) 2005-06-28 US claimed
US-20030207823-A1 Novel diabetes imaging probes CARBOMER, INC. 2003-11-06 US claimed
WO-2003086563-A2 DIABETES IMAGING PROBES CARBOMER, INC. (US) 2003-10-23 WO claimed
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2025-12-02 US disclosed
US-12440833-B2 Sample containers adapted for acoustic ejections and sample preservation and methods thereof LABCYTE INC. (US) 2025-10-14 US disclosed
EP-3983020-B1 AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO TAGWORKS PHARMACEUTICALS B V (NL) 2024-06-26 EP disclosed
WO-2023165987-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2023-09-07 WO disclosed
US-20230235087-A1 ANTI-GD2 SADA CONJUGATES AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER 2023-07-27 US disclosed
WO-2023118195-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2023-06-29 WO disclosed
WO-2003086563-A2 DIABETES IMAGING PROBES CARBOMER, INC. (US) 2003-10-23 WO disclosed
US-20030059368-A1 Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products BIOPAL, INC. 2003-03-27 US disclosed
WO-2002062397-A2 CHELATES OF METALS WHICH CAN BE ACTIVATED BY NEUTRONS AND THEIR USE FOR THE MEASUREMENT OF LABELED SPECIMENS BIOPHYSICS ASSAY LABORATORY, INC. (US) 2002-08-15 WO disclosed
EP-0523572-B1 Nuclear magnetic resonance imaging agent NIHON MEDIPHYSICS CO LTD (JP) 1996-10-02 EP disclosed
US-5271929-A Nuclear magnetic resonance imaging agent comprising a di-aldehyde complex NIHON MEDI-PHYSICS CO., LTD. (JP) 1993-12-21 US disclosed
EP-0523572-A1 Nuclear magnetic resonance imaging agent NIHON MEDI-PHYSICS CO., LTD. (JP) 1993-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 FOLH1 526/4885CHIT1 2780/4885DPP4 167/4885
US-20030207823-A1 Novel diabetes imaging probes IAPP, GPR119, DPP4 FOLH1 716/4885CHIT1 1632/4885DPP4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.