SCHEMBL1996277

SCHEMBL1996277

O=C(Oc1ccc(OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)cc1)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.48
LMNA P02545 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.39
ELANE P08246 3/20 0.38
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
PTGS2 P35354 1/20 0.34
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ESR1 P03372 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 2/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27844553 0.93 PDE4A (0.43) PDE4ALMNAL3MBTL1TDP1ELANE
SCHEMBL27844555 0.93 PDE4A (0.43) PDE4ALMNAL3MBTL1TDP1ELANE
SCHEMBL6726577 0.91 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1ELANE
SCHEMBL428554 0.85 KMT2A (0.54) LMNATDP1KMT2AMEN1ALDH1A1
SCHEMBL29206123 0.83 PTPN1 (0.47) PDE4ALMNATDP1USP2SLCO1B1
SCHEMBL30158422 0.83 PDE4A (0.43) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28362734 0.81 ALDH1A1 (0.40) PDE4ALMNATDP1PTGS2KMT2A
SCHEMBL4395508 0.76 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6854159 0.76 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL1326070 0.76 PDE4A (0.60) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210205201-A1 ENZYMATIC SYSTEM-CONTAINING COSMETIC COMPOSITIONS RAKUTO BIO TECHNOLOGIES LTD. (IL) 2021-07-08 US disclosed
US-10980730-B2 Enzymatic system-containing cosmetic compositions RAKUTO BIO TECHNOLOGIES LTD. (IL) 2021-04-20 US disclosed
EP-3626310-A1 ENZYMATIC SYSTEM CONTAINING COSMETIC COMPOSITIONS Rakuto Bio Technologies Ltd. (IL) 2020-03-25 EP disclosed
EP-3003493-B1 ENZYMATIC SYSTEM-CONTAINING COSMETIC COMPOSITIONS RAKUTO BIO TECH LTD (IL) 2019-09-25 EP disclosed
CN-108524320-A Cosmetic composition containing enzyme system 洛东生物科技有限公司 2018-09-14 CN disclosed
US-20170273885-A1 METHODS OF PRODUCING LIGNIN PEROXIDASE AND ITS USE IN SKIN AND HAIR LIGHTENING R.B.T (RAKUTO BIO TECHNOLOGIES) LTD. (IL) 2017-09-28 US disclosed
US-9693946-B2 Methods of producing lignin peroxidase and its use in skin and hair lightening R.B.T. (RAKUTO BIO TECHNOLOGIES) LTD. (IL) 2017-07-04 US disclosed
CN-104911238-B A kind of method that biofermentation produces α ursin 南京泛成生物化工有限公司 2017-05-31 CN disclosed
US-20160101034-A1 ENZYMATIC SYSTEM-CONTAINING COSMETIC COMPOSITIONS RAKUTO BIO TECHNOLOGIES LTD. (IL) 2016-04-14 US disclosed
EP-3003493-A2 ENZYMATIC SYSTEM-CONTAINING COSMETIC COMPOSITIONS Rakuto Bio Technologies Ltd. (IL) 2016-04-13 EP disclosed
US-7422734-B2 Applying lignin peroxidase enzyme to skin or hair for oxidizing a pigment contained within cells R.B.T. (RAKUTO BIO TECHNOLOGIES) LTD. (IL) 2008-09-09 US disclosed
CN-100402016-C Method for producing lignin peroxidase and its use for skin and hair lightening R B T RAKUTO BIO TECHNOLOGIES (IL) 2008-07-16 CN disclosed
EP-1583512-A4 METHODS OF PRODUCING LIGNIN PEROXIDASE AND ITS USE IN SKIN AND HAIR LIGHTENING R B T RAKUTO BIO TECHNOLOGIES (IL) 2006-06-21 EP disclosed
CN-1747712-A Method for producing lignin peroxidase and its use for skin and hair lightening R B T RAKUTO BIO TECHNOLOGIES (IL) 2006-03-15 CN disclosed
US-20060051305-A1 Applying lignin peroxidase enzyme to skin or hair for oxidizing a pigment contained within cells R.B.T. (RAKUTO BIO TECHNOLOGIES) LTD. (IL) 2006-03-09 US disclosed
EP-1583512-A2 METHODS OF PRODUCING LIGNIN PEROXIDASE AND ITS USE IN SKIN AND HAIR LIGHTENING R.B.T. (Rakuto Bio Technologies) Ltd. (IL) 2005-10-12 EP disclosed
WO-2004052275-A2 METHODS OF PRODUCING LIGNIN PEROXIDASE AND ITS USE IN SKIN AND HAIR LIGHTENING R.B.T. (RAKUTO BIO TECHNOLOGIES) LTD. (IL) 2004-06-24 WO disclosed
EP-0897717-B1 Whitening skin cosmetic composition and melanogenic inhibitor agent containing such cosmetic composition EXSYMOL SA (MC) 2004-06-09 EP disclosed
US-6280715-B1 APPLYING AMINOORGANOPHOSPHONIC ACID OR -PHOSPHINIC ACID DERIVATIVE AND ORGANOSILICON COMPOUND EXSYMOL S.A.M. (MC) 2001-08-28 US disclosed
EP-0897717-A2 Whitening skin cosmetic composition and melanogenic inhibitor agent containing such cosmetic composition EXSYMOL S.A.M. (MC) 1999-02-24 EP disclosed