Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426347 | 0.87 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL1996277 | 0.85 | PDE4A (0.48) | KMT2AMEN1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL427933 | 0.85 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL422235 | 0.85 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL425278 | 0.82 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL27844553 | 0.80 | PDE4A (0.43) | KMT2ACYP1A2LMNATDP1ALDH1A1 | |
| SCHEMBL27844555 | 0.80 | PDE4A (0.43) | KMT2ACYP1A2LMNATDP1ALDH1A1 | |
| SCHEMBL6726577 | 0.78 | PDE4A (0.48) | HSD17B10CYP1A2LMNATDP1ALDH1A1 | |
| Mannitol SCHEMBL28233068 | 0.78 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2HSD17B10CYP1A2 | |
| SCHEMBL16788260 | 0.76 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722864-B2 | Glycosylated acetaminophen pro-drug analogs | NuTek Pharma Ltd. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130217640-A1 | GLYCOSYLATED ACETAMINOPHEN PRO-DRUG | NuTek Pharma Ltd. | 2013-08-22 | — | — | US | disclosed |
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | NuTek Pharma Ltd. | 2012-01-26 | — | — | US | disclosed |
| WO-2012012339-A2 | GLYCOSYLATED ACETAMINOPHEN PRO-DRUG ANALOGS | NuTek Pharma Ltd. (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022012-A1 | Glycosylated Acetaminophen Pro-Drug Analogs | UGT1A3, GCG, UGT1A1 | KMT2A 4128/4885MEN1 4056/4885SMN1; SMN2 4141/4885 |
| US-20130217640-A1 | GLYCOSYLATED ACETAMINOPHEN PRO-DRUG | UGT1A3, GCG, UGGT1 | KMT2A 4023/4885MEN1 4207/4885SMN1; SMN2 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.