Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.50 |
| ▸ | PIM1 | P11309 | 4/20 | 0.50 |
| ▸ | PRKACA | P17612 | 4/20 | 0.50 |
| ▸ | GSK3A | P49840 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.50 |
| ▸ | CLK2 | P49760 | 3/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.50 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980400 | 1.00 | LMNA (0.64) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL19964559 | 0.86 | PIM1 (0.54) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL700588 | 0.84 | LMNA (0.66) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL29481855 | 0.84 | LMNA (0.66) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL21406460 | 0.82 | LMNA (0.64) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL30193075 | 0.82 | LMNA (0.64) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL121775 | 0.82 | LMNA (0.69) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL13709516 | 0.82 | F9 (0.59) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL19951048 | 0.81 | LMNA (0.59) | LMNAMEN1RAB9AKMT2ADYRK1A | |
| SCHEMBL29069457 | 0.81 | MEN1 (0.65) | LMNAMEN1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730995-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-116730995-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |