Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 8/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21406460 | 1.00 | LMNA (0.64) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL22479260 | 0.86 | LMNA (0.47) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL700588 | 0.84 | LMNA (0.66) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL29481855 | 0.84 | LMNA (0.66) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL19964501 | 0.82 | LMNA (0.64) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL30980400 | 0.82 | LMNA (0.64) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL121775 | 0.82 | LMNA (0.69) | LMNAMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL17267445 | 0.80 | CHRNA7 (0.46) | LMNACLK1DYRK1ADYRK1BHDAC1 | |
| SCHEMBL19756728 | 0.79 | MEN1 (0.49) | LMNAMEN1RAB9AKMT2ACLK1 | |
| SCHEMBL17149287 | 0.79 | CYP2A6 (0.50) | LMNAMEN1RAB9AKMT2ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |