Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002400 | 0.92 | HTR6 (0.41) | HTR6KDM4ECYP3A4HTR2AHTR2C | |
| Trifluoroacetic Acid SCHEMBL1998224 | 0.91 | HTR6 (0.40) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL1992942 | 0.85 | HTR6 (0.41) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL2000044 | 0.84 | HTR6 (0.39) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL1994879 | 0.84 | KDM4E (0.36) | HTR6KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL2001693 | 0.83 | HTR6 (0.46) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL1999781 | 0.78 | HTR6 (0.46) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| SCHEMBL1995792 | 0.75 | HTR6 (0.36) | HTR6KDM4ECYP3A4HTR2AHTR2C | |
| SCHEMBL1997804 | 0.75 | HTR6 (0.43) | HTR6CYP3A4HTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL1997380 | 0.75 | HTR6 (0.38) | HTR6CYP3A4HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960374-B2 | e.g. 2,5-methylene-9-(phenylsulfonyl)-1,2,3,4,5,9-hexahydro[1,5]oxazocino[3,2-e]indole; serotonin receptors antagonist or partial agonist; metabolic diseases, e.g. obesity, insulin resisitance, type 2 diabetes, eating disorders; antidepressant, anxiolytic agent; cosmetics | PROXIMAGEN LIMITED (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20080176829-A1 | Compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176829-A1 | Compounds | HTR6, HTR1B, HTR1A | HTR6 1/4885KDM4E 3829/4885CYP3A4 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.