Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478663 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2NAMPTCACNA1HCACNA1BCACNA1C | |
| SCHEMBL30632885 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2NAMPTCACNA1HCACNA1BCACNA1C | |
| SCHEMBL30469092 | 0.82 | KDM4A (0.54) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL25677972 | 0.82 | KDM4A (0.54) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL30920730 | 0.80 | NQO2 (0.48) | SMN1; SMN2CACNA1HCACNA1BCACNA1CKDM4A | |
| SCHEMBL12024521 | 0.79 | NR3C1 (0.43) | NR3C1NR3C2PGRCYP3A4DAO | |
| SCHEMBL30759266 | 0.79 | KDM4A (0.48) | SMN1; SMN2NAMPTCACNA1HCACNA1BCACNA1C | |
| SCHEMBL28593575 | 0.78 | F2 (0.54) | SMN1; SMN2MASP2NAMPTCYP3A4 | |
| SCHEMBL30387402 | 0.78 | F2 (0.54) | SMN1; SMN2MASP2NAMPTCYP3A4 | |
| SCHEMBL23478384 | 0.78 | F2 (0.54) | SMN1; SMN2MASP2NAMPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |