⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976517 | 0.83 | NOS1 (0.31) | — | |
| SCHEMBL23236817 | 0.81 | NOS1 (0.32) | — | |
| SCHEMBL22984074 | 0.67 | HKDC1 (0.31) | — | |
| SCHEMBL21398475 | 0.65 | NPC1 (0.33) | — | |
| SCHEMBL23236828 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL20630126 | 0.62 | — | — | |
| SCHEMBL13820156 | 0.61 | NOS1 (0.39) | — | |
| SCHEMBL26415287 | 0.59 | — | — | |
| SCHEMBL26415302 | 0.59 | — | — | |
| SCHEMBL22245954 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10365285-B2 | Reagents for directed biomarker signal amplification | SIRIGEN II LIMITED (GB) | 2019-07-30 | — | — | US | disclosed |
| US-20180074067-A1 | Novel Reagents for Directed Biomarker Signal Amplification | SIRIGEN GROUP LIMITED (GB) | 2018-03-15 | — | — | US | disclosed |