Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | CDC42 | P60953 | 1/20 | 0.38 |
| ▸ | RAC1 | P63000 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18627231 | 0.87 | ALOX5 (0.47) | ALOX5MEN1KMT2AAOC3ALDH1A1 | |
| SCHEMBL23095298 | 0.85 | ALOX5 (0.43) | ALOX5HPGDTAS1R3TAS1R1MEN1 | |
| SCHEMBL18627263 | 0.78 | ALOX5 (0.46) | ALOX5HPGDMEN1KMT2AAOC3 | |
| SCHEMBL18627485 | 0.74 | ALOX5 (0.45) | ALOX5MEN1KMT2AAOC3ALDH1A1 | |
| SCHEMBL12434956 | 0.69 | MEN1 (0.48) | ALOX5MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL956546 | 0.69 | MEN1 (0.48) | ALOX5HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL14380841 | 0.69 | ALOX5 (0.46) | ALOX5SMN1; SMN2MEN1KMT2AAOC3 | |
| SCHEMBL21025254 | 0.69 | ALOX5 (0.55) | ALOX5MEN1KMT2AAOC3ALDH1A1 | |
| SCHEMBL13899483 | 0.68 | MEN1 (0.47) | ALOX5HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20373312 | 0.67 | LDHA (0.46) | HPGDMEN1KMT2AALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072744-A1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072744-A1 | HETEROARYL SYK INHIBITORS | SYK, BTK, CD40 | ALOX5 1323/4885HPGD 2419/4885TP53 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.