Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.54 |
| ▸ | ITGAV | P06756 | 20/20 | 0.54 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224024 | 0.80 | ITGAV (0.65) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL20021718 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6729630 | 0.77 | ITGAV (0.59) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL20025156 | 0.76 | ITGAV (0.69) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4786884 | 0.75 | ITGB3 (0.71) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL19953598 | 0.74 | ITGAV (0.73) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL19953599 | 0.74 | ITGAV (0.73) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL17495214 | 0.74 | ITGAV (0.55) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL8267444 | 0.73 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL20025321 | 0.73 | ITGAV (0.70) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049068-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2018-03-15 | — | — | WO | disclosed |