Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.71 |
| ▸ | ITGAV | P06756 | 20/20 | 0.71 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.71 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.66 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224024 | 0.95 | ITGAV (0.65) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4200668 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4242685 | 0.85 | ITGB1 (0.64) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6729630 | 0.84 | ITGAV (0.59) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6178864 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL6178862 | 0.83 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL14270778 | 0.83 | ITGAV (0.79) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4241332 | 0.83 | ITGAV (0.69) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4193839 | 0.81 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB5ITGA2B | |
| SCHEMBL4904824 | 0.81 | ITGAV (0.69) | ITGB3ITGAVITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093064-A1 | L-ALANINE DERIVATIVES AS α5 BETA 1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-08-07 | — | — | WO | disclosed |