Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487643 | 0.94 | ACHE (0.90) | ACHEBCHE | |
| SCHEMBL27855737 | 0.93 | ACHE (0.93) | ACHEBCHE | |
| SCHEMBL5485655 | 0.90 | ACHE (0.97) | ACHEBCHE | |
| SCHEMBL5945371 | 0.89 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL1537859 | 0.89 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5945380 | 0.89 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5489233 | 0.89 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL5486217 | 0.89 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL13480729 | 0.89 | BCHE (0.92) | ACHEBCHE | |
| SCHEMBL27995331 | 0.87 | BCHE (0.75) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017476-B2 | 1,4-bis(3-aminopropyl)piperazine derivative and its use | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2018-07-10 | — | — | US | disclosed |
| US-20180072679-A1 | NOVEL 1,4-BIS(3-AMINOPROPYL)PIPERAZINE DERIVATIVE AND ITS USE | INSERM ( INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072679-A1 | NOVEL 1,4-BIS(3-AMINOPROPYL)PIPERAZINE DERIVATIVE AND ITS USE | MAPT, PSEN1, PSEN2 | ACHE 413/4885BCHE 232/4885 |
| US-10017476-B2 | 1,4-bis(3-aminopropyl)piperazine derivative and its use | MAPT, PSEN1, PSEN2 | ACHE 146/4885BCHE 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.