SCHEMBL1996614

SCHEMBL1996614

Nc1nc(N)c(C(=O)NC(=NCCCCc2ccc(OCC(O)CO)cc2)NCS(=O)(=O)O)nc1Cl

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15092805 0.89 SCNN1A (0.75) SCNN1A
552-02 Free Base SCHEMBL2015164 0.86 SCNN1A (1.00) SCNN1A
SCHEMBL16499025 0.83 SCNN1A (0.70) SCNN1A
SCHEMBL16499028 0.83 SCNN1A (0.70) SCNN1A
SCHEMBL916348 0.83 SCNN1A (0.94) SCNN1A
552-02 Free Base SCHEMBL15092803 0.83 SCNN1A (0.67) SCNN1A
552-02 Free Base SCHEMBL29615808 0.83 SCNN1A (0.67) SCNN1A
552-02 Free Base SCHEMBL9913774 0.81 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL2015162 0.81 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL9913757 0.81 SCNN1A (0.71) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11077263-B2 Disposable ampoule for an aerosol generating device PARI PHARMA GMBH (DE) 2021-08-03 US disclosed
US-9687627-B2 Nebuliser for ventilation machines and a ventilation machine comprising such a nebuliser PARI PHARMA GMBH (DE) 2017-06-27 US disclosed
US-20160199597-A1 DISPOSABLE AMPOULE FOR AN AEROSOL GENERATING DEVICE PARI PHARMA GMBH (DE) 2016-07-14 US disclosed
US-9265900-B2 Disposable ampoule for an aerosol generating device PARI PHARMA GMBH (DE) 2016-02-23 US disclosed
US-20150306334-A1 NEBULISER FOR VENTILATION MACHINES AND A VENTILATION MACHINE COMPRISING SUCH A NEBULISER PARI PHARMA GMBH (DE) 2015-10-29 US disclosed
US-9095676-B2 Nebuliser for ventilation machines and a ventilation machine comprising such a nebuliser PARI PHARMA GMBH (DE) 2015-08-04 US disclosed
US-8720435-B2 Nebuliser for ventilation machines and a ventilation machine comprising such a nebuliser PARI PHARMA GMBH (DE) 2014-05-13 US disclosed
US-20130174840-A1 NEBULISER FOR VENTILATION MACHINES AND A VENTILATION MACHINE COMPRISING SUCH A NEBULISER PARI PHARMA GMBH (DE) 2013-07-11 US disclosed
US-20110146670-A1 NEBULISER FOR VENTILATION MACHINES AND A VENTILATION MACHINE COMPRISING SUCH A NEBULISER PARI PHARMA GMBH (DE) 2011-06-23 US disclosed
US-20090137950-A1 DISPOSABLE AMPOULE FOR AN AEROSOL GENERATING DEVICE PARI PHARMA GMBH (DE) 2009-05-28 US disclosed