Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 17/20 | 0.65 |
| ▸ | CDK4 | P11802 | 2/20 | 0.65 |
| ▸ | CCND3 | P30281 | 2/20 | 0.65 |
| ▸ | CCND1 | P24385 | 13/20 | 0.63 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19966302 | 0.90 | CDK6 (0.66) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966573 | 0.87 | CDK6 (0.64) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966649 | 0.85 | CDK6 (0.63) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966544 | 0.85 | CDK6 (0.71) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL17477168 | 0.84 | CDK6 (0.75) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL17489238 | 0.82 | CDK6 (0.74) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19209837 | 0.81 | CDK6 (0.69) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966382 | 0.81 | CDK6 (0.71) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966325 | 0.80 | CDK6 (0.61) | CDK6CDK4CCND3CCND1DYRK2 | |
| SCHEMBL19966456 | 0.80 | CDK6 (0.56) | CDK6CDK4CCND3CCND1DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045957-A1 | CDK4/6 INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2018-03-15 | — | — | WO | disclosed |