SCHEMBL19966686

SCHEMBL19966686

O=C1OCc2cc(-c3ccc4c(c3)C(=O)OC4=O)ccc21

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRF1 P14222 16/20 0.61
MAPT P10636 2/20 0.54
LMNA P02545 2/20 0.54
GAA P10253 1/20 0.54
ACHE P22303 1/20 0.49
RECQL P46063 1/20 0.49
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19607528 0.98 PRF1 (0.59) PRF1MAPTLMNAGAAACHE
SCHEMBL22300002 0.90 PRF1 (0.49) PRF1MAPTLMNAGAARECQL
SCHEMBL23452986 0.87 PRF1 (0.48) PRF1MAPTLMNAGAAACHE
SCHEMBL13469961 0.82 PRF1 (0.65) PRF1MAPTLMNAGAAACHE
SCHEMBL169305 0.81 ALOX15 (0.57) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL741462 0.81 ALOX15 (0.57) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL29358248 0.81 ALOX15 (0.57) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL29359977 0.81 ALOX15 (0.57) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL29423347 0.81 ALOX15 (0.57) MAPTLMNAMAOAMAOBALDH1A1
SCHEMBL16573996 0.79 PRF1 (0.61) PRF1MAPTLMNAGAAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200317963-A1 DETACHABLE LAYER-FORMING COMPOSITION AND DETACHABLE LAYER NISSAN CHEMICAL CORPORATION (JP) 2020-10-08 US disclosed
US-10431858-B2 Systems, structures and materials for electrochemical device thermal management LATENT HEAT SOLUTIONS, LLC 2019-10-01 US disclosed
US-20180072882-A1 OPTICAL COMPENSATION FILM HAVING REVERSED WAVELENGTH DISPERSION AKRON POLYMER SYSTEMS, INC. (US) 2018-03-15 US disclosed