SCHEMBL1996754

SCHEMBL1996754

CCNCCCC[SiH](OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48
MEN1 O00255 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 2/20 0.42
KDM1A O60341 5/20 0.40
SAT1 P21673 3/20 0.36
ALDH1A1 P00352 1/20 0.33
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15360480 0.98 CYP2C19 (0.46) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL3912318 0.93 CYP2C19 (0.46) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL614715 0.85 TSHR (0.42) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL554524 0.85 TSHR (0.48) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL4652048 0.84 TSHR (0.41) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL4237452 0.84 CYP2C19 (0.38) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL975253 0.84 CYP2C19 (0.38) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL37493 0.83 CA12 (0.42) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL15361157 0.83 TSHR (0.46) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL7158315 0.83 CYP1A2 (0.31) CYP2C19CYP1A2MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019004922-A1 COATING SYSTEM, METHOD OF APPLICATION AND KIT FOR USE Bona AB (SE) 2019-01-03 WO claimed
WO-2019004922-A1 COATING SYSTEM, METHOD OF APPLICATION AND KIT FOR USE Bona AB (SE) 2019-01-03 WO disclosed
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
EP-2660244-B1 Organoxysilane compounds having silyl-protected secondary amino group and making method SHINETSU CHEMICAL CO (JP) 2016-02-10 EP disclosed
US-9024051-B2 Organoxysilane compounds having silyl-protected secondary amino group and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
US-20130296593-A1 ORGANOXYSILANE COMPOUNDS HAVING SILYL-PROTECTED SECONDARY AMINO GROUP AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-07 US disclosed
EP-2660244-A1 Organoxysilane compounds having silyl-protected secondary amino group and making method Shin-Etsu Chemical Co., Ltd. (JP) 2013-11-06 EP disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296593-A1 ORGANOXYSILANE COMPOUNDS HAVING SILYL-PROTECTED SECONDARY AMINO GROUP AND MAKING METHOD AS3MT, SUGT1, PNMT CYP2C19 4290/4885CYP1A2 3328/4885MEN1 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.