SCHEMBL4237452

SCHEMBL4237452

CCNCC[SiH](OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.38
MEN1 O00255 1/20 0.38
GLA P06280 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
TP53 P04637 1/20 0.33
SAT1 P21673 1/20 0.31
KDM1A O60341 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912318 0.86 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL1996754 0.84 CYP2C19 (0.48) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL15360480 0.82 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL4652048 0.78 TSHR (0.41) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL16782934 0.77 CYP2C19 (0.39) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL3452062 0.77 EPHX1 (0.31)
SCHEMBL8059483 0.76 CA12 (0.46) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL975253 0.75 CYP2C19 (0.38) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL555221 0.75 ADH1B (0.46)
SCHEMBL707438 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8080500-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2011-12-20 US disclosed
US-20090029888-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. 2009-01-29 US disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
EP-1907517-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS King Industries, Inc. (US) 2008-04-09 EP disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed