Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998282 | 0.81 | L3MBTL1 (0.65) | L3MBTL1HTR6PKMKMT2AMEN1 | |
| SCHEMBL5740608 | 0.76 | L3MBTL1 (1.00) | L3MBTL1HTR6PKMKDM4EKMT2A | |
| SCHEMBL28935600 | 0.76 | L3MBTL1 (0.55) | L3MBTL1HTR6PKMKDM4EKMT2A | |
| SCHEMBL3006668 | 0.75 | L3MBTL1 (0.72) | L3MBTL1HTR6PKM | |
| SCHEMBL30275137 | 0.75 | L3MBTL1 (0.72) | L3MBTL1HTR6PKMKMT2AMEN1 | |
| SCHEMBL6638305 | 0.75 | L3MBTL1 (0.72) | L3MBTL1HTR6SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4265552 | 0.75 | L3MBTL1 (0.72) | L3MBTL1HTR6PKMMAPTSMN1; SMN2 | |
| SCHEMBL28935725 | 0.74 | L3MBTL1 (0.56) | L3MBTL1HTR6PKMKDM4EKMT2A | |
| SCHEMBL28935720 | 0.73 | L3MBTL1 (0.57) | L3MBTL1HTR6KDM4EKMT2AMEN1 | |
| SCHEMBL1996984 | 0.72 | L3MBTL1 (0.65) | L3MBTL1HTR6PKMKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885HTR6 368/4885PKM 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.