SCHEMBL1996784

SCHEMBL1996784

CC(O)c1c(F)c(F)cc(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA4 P22748 2/20 0.36
CES2 O00748 4/20 0.34
CES1 P23141 4/20 0.34
PDE2A O00408 1/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CYP11B2 P19099 1/20 0.30
DPP4 P27487 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996066 0.85 MEN1 (0.35) MEN1KMT2ACA1CA2CA4
SCHEMBL31015973 0.84 MEN1 (0.33) MEN1KMT2A
SCHEMBL25241633 0.84 MEN1 (0.33) MEN1KMT2A
SCHEMBL27372519 0.80 CA1 (0.33) CA1CA2CA4CES2CES1
SCHEMBL22129200 0.80 MEN1 (0.34) MEN1KMT2AALDH1A1
SCHEMBL9003976 0.78 CA1 (0.33) CA1CA2CA4CES2CES1
SCHEMBL5327956 0.77 MEN1 (0.33) MEN1KMT2AALDH1A1
SCHEMBL1756535 0.77 MEN1 (0.33) MEN1KMT2AALDH1A1
SCHEMBL2002035 0.77 MEN1 (0.36) MEN1KMT2ACES2CES1PDE2A
SCHEMBL6454749 0.77 CYP11B2 (0.36) MEN1KMT2ACES2CES1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-111542575-B Coating composition and optical article having hard coating film 株式会社德山 2022-12-23 CN disclosed
US-20210040335-A1 COATING COMPOSITION AND OPTICAL ARTICLE HAVING A HARD COAT FILM TOKUYAMA CORPORATION (JP) 2021-02-11 US disclosed
EP-3747966-A1 COATING COMPOSITION AND OPTICAL ARTICLE HAVING HARD COAT FILM Tokuyama Corporation (JP) 2020-12-09 EP disclosed
CN-111542575-A Coating composition and optical article having hard coat film 株式会社德山 2020-08-14 CN disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-4939172-A Novel cyclopropane carboxylates ROUSSEL UCLAF (FR) 1990-07-03 US disclosed