SCHEMBL1756535

SCHEMBL1756535

CC(O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5327956 1.00 MEN1 (0.33) MEN1KMT2AALDH1A1LMNA
SCHEMBL22129200 0.97 MEN1 (0.34) MEN1KMT2AALDH1A1LMNA
SCHEMBL9810380 0.85 TAS1R3 (0.38) MEN1KMT2A
SCHEMBL31643990 0.85 MEN1 (0.31) MEN1KMT2A
SCHEMBL10585715 0.83
SCHEMBL9252402 0.81 CA12 (0.38) ALDH1A1
SCHEMBL10341798 0.79 SMN1; SMN2 (0.34) MEN1KMT2AALDH1A1
SCHEMBL28069408 0.79 HSD17B10 (0.32)
SCHEMBL9810424 0.77
SCHEMBL1996784 0.77 MEN1 (0.37) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0337820-B1 PENTAFLUOROPHENYL DERIVATIVES, METHODS OF PRODUCTION OF SUCH DERIVATIVES INCLUDING OPTICALLY ACTIVE DERIVATIVES, AND METHOD OF OPTICAL RESOLUTION OF CHIRAL CARBOXYLIC ACIDS NIKKO KYODO CO., LTD. (JP) 1993-07-28 EP claimed
US-5041641-A Pentafluorophenyl derivatives, methods of production thereof, and method of optical resolution of chiral carboxylic acids NIPPON MINING COMPANY LIMITED (JP) 1991-08-20 US claimed
EP-0337820-A1 Pentafluorophenyl derivatives, methods of production of such derivatives including optically active derivatives, and method of optical resolution of chiral carboxylic acids NIKKO KYODO CO., LTD. (JP) 1989-10-18 EP claimed
JP-1316332-A None JP disclosed
JP-2225432-A None JP disclosed
JP-1316331-A None JP disclosed
JP-2072149-A None JP disclosed
WO-2024117202-A1 POROUS BODY AND METHOD FOR PRODUCING POROUS BODY 東洋製罐グループホールディングス株式会社 2024-06-06 WO disclosed
CN-114262441-A Bisphenol compound containing fluorophenylsiloxane side chain, vulcanizing agent system for fluororubber and fluorosilicone rubber 浙江加诚新材料股份有限公司 2022-04-01 CN disclosed
CN-107922543-B Copolymer, method for producing same, resin material for coating electric wire, and electric wire AGC株式会社 2021-09-03 CN disclosed
JP-H0272149-A 1-(PENTAFLUOROPHENYL)ETHYL=SULFONATE, PRODUCTION THEREOF AND SEPARATION OF CHIRAL CARBOXYLIC ACID OPTICAL ISOMER NIPPON MINING CO LTD 1990-03-12 JP disclosed
JP-H01316332-A OPTICALLY ACTIVE PENTAFLUOROPHENYL DERIVATIVE AND PRODUCTION THEREOF NIPPON MINING CO LTD 1989-12-21 JP disclosed
JP-H01316331-A PRODUCTION OF OPTICALLY ACTIVE 1-(PENTAFLUOROPHENYL) ETHANOL NIPPON MINING CO LTD 1989-12-21 JP disclosed
WO-1989012225-A1 HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION HEWLETT-PACKARD COMPANY (US) 1989-12-14 WO disclosed
EP-0337820-A1 Pentafluorophenyl derivatives, methods of production of such derivatives including optically active derivatives, and method of optical resolution of chiral carboxylic acids NIKKO KYODO CO., LTD. (JP) 1989-10-18 EP disclosed
US-4822426-A BLEND OF ORGANOMETALLIC COMPOUNDS RESIN AND FLUORINE COMPOUND TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-04-18 US disclosed
EP-0010879-B1 HALOGENATED ESTERS OF CYCLOPROPANE ACIDS, THEIR PREPARATION, COMPOSITIONS AND USE AS PESTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-27 EP disclosed
EP-0010879-A1 Halogenated esters of cyclopropane acids, their preparation, compositions and use as pesticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-05-14 EP disclosed