Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.60 |
| ▸ | ACR | P10323 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956570 | 0.89 | KMT2A (0.56) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL11302255 | 0.87 | LMNA (0.52) | PRSS1ACRMAPTTDP1L3MBTL1 | |
| SCHEMBL7328271 | 0.86 | ACR (0.58) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL11313701 | 0.85 | KMT2A (0.54) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7330789 | 0.85 | ACR (0.59) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL3675089 | 0.85 | KMT2A (0.69) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL11316711 | 0.84 | PARP10 (0.61) | PRSS1ACRL3MBTL1KMT2AMEN1 | |
| SCHEMBL10600357 | 0.84 | PRSS1 (0.68) | PRSS1ACRMAPTTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7321119 | 0.83 | PRSS1 (0.70) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL1645313 | 0.83 | KMT2A (0.44) | PRSS1ACRMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960459-B2 | Curable composition | KANEKA CORPORATION (JP) | 2011-06-14 | — | — | US | disclosed |
| EP-1990371-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20090186993-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1990371-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2008-11-12 | — | — | EP | disclosed |