Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 12/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179643 | 0.73 | GRM5 (0.63) | MAPTMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13186281 | 0.72 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL20179642 | 0.71 | ELANE (0.42) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL20165273 | 0.71 | GRM5 (0.54) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL13998362 | 0.71 | ELANE (0.76) | ELANEHSD17B10 | |
| SCHEMBL18456063 | 0.70 | MAPT (0.53) | MAPTMEN1KMT2AELANEHSD17B10 | |
| SCHEMBL17861951 | 0.69 | ESRRB (0.49) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL22369614 | 0.69 | ELANE (0.86) | ELANE | |
| SCHEMBL10064126 | 0.68 | MAPT (0.60) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL30953875 | 0.68 | KDM4E (0.52) | ESR1ESR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049042-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCERS BY INHIBITING ESTROGEN SIGNALING IN MYELOID-DERIVED SUPPRESSOR CELLS | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2018-03-15 | — | — | WO | disclosed |