Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.42 |
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273758 | 0.78 | ELANE (0.44) | ELANEESR1MEN1KMT2A | |
| SCHEMBL20165320 | 0.77 | ESR1 (0.50) | ESR1 | |
| SCHEMBL20165318 | 0.77 | ESR1 (0.50) | ESR1 | |
| SCHEMBL20179807 | 0.76 | MAPT (0.38) | ELANEESR1ESR2MEN1KMT2A | |
| SCHEMBL20179643 | 0.74 | GRM5 (0.63) | MEN1KMT2AMAPTGRM5HSD17B10 | |
| SCHEMBL20165456 | 0.74 | ELANE (0.38) | ELANEESR1ESR2MEN1KMT2A | |
| SCHEMBL20179806 | 0.74 | ELANE (0.38) | ELANEESR1ESR2MEN1KMT2A | |
| SCHEMBL20165273 | 0.72 | GRM5 (0.54) | ELANEESR1ESR2MEN1KMT2A | |
| SCHEMBL19968965 | 0.71 | ESR1 (0.48) | ELANEESR1ESR2MEN1KMT2A | |
| SCHEMBL22536181 | 0.70 | CYP19A1 (0.47) | ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |