Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30953739 | 0.82 | ADORA1 (0.61) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953827 | 0.76 | LMNA (0.48) | KDM4EALDH1A1LMNAGAAHTT | |
| SCHEMBL30953763 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953632 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953677 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL30953825 | 0.72 | KDM4E (0.60) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL15075787 | 0.70 | KDM4E (0.56) | KDM4EALDH1A1LMNAGAAADORA1 | |
| SCHEMBL9206837 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1LMNAGAAHTT | |
| SCHEMBL20179643 | 0.69 | GRM5 (0.63) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| Iodide SCHEMBL4960911 | 0.69 | KDM4E (0.97) | KDM4EALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |