Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996937 | 0.93 | FFAR1 (0.57) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL2003964 | 0.93 | ALDH1A1 (0.49) | VDRPPARDFFAR1FFAR4ALDH1A1 | |
| SCHEMBL2007896 | 0.86 | ALDH1A1 (0.51) | PPARDFFAR1FFAR4ALDH1A1MAPK1 | |
| SCHEMBL2002627 | 0.85 | FFAR1 (0.57) | PPARDFFAR1FFAR4AKR1B1ALDH1A1 | |
| SCHEMBL1747259 | 0.79 | MEN1 (0.48) | VDRPPARDFFAR1FFAR4ALDH1A1 | |
| SCHEMBL1744991 | 0.78 | FFAR1 (0.77) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745339 | 0.77 | FFAR1 (0.62) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745420 | 0.75 | FFAR1 (0.60) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745242 | 0.75 | MAPT (0.52) | VDRPPARDFFAR1FFAR4ALDH1A1 | |
| SCHEMBL1745514 | 0.75 | PPARD (0.46) | VDRPPARDFFAR1FFAR4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |