SCHEMBL1745514

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1744702	0.92	PPARD (0.54)	PPARDPPARGFFAR1PPARAFFAR4
	SCHEMBL1747259	0.89	MEN1 (0.48)	PPARDPPARGMEN1KMT2ALMNA
	SCHEMBL1746697	0.87	PPARD (0.44)	PPARDKARS1PPARGVDRFFAR1
	SCHEMBL1745481	0.86	NPSR1 (0.47)	PPARDMEN1KMT2ANPSR1VDR
	SCHEMBL3913901	0.84	VDR (0.48)	PPARDPPARGVDRFFAR1BCHE
	SCHEMBL1745335	0.82	PPARD (0.41)	PPARDKARS1PPARGKMT2ALMNA
	SCHEMBL5407843	0.81	FFAR1 (0.53)	PPARGFFAR1PPARA
	SCHEMBL3917024	0.81	NPSR1 (0.53)	PPARDKARS1MEN1KMT2ANPSR1
	SCHEMBL1746854	0.80	FFAR1 (0.56)	PPARDMEN1KMT2ALMNAPOLB
	SCHEMBL1745386	0.80	ATP4A (0.45)	PPARDMEN1KMT2ANPSR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.