SCHEMBL1997039

SCHEMBL1997039

Cc1cccc(N=Nc2ccc(C)c(C)c2N=Nc2c(O)ccc3ccccc23)c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.61
MAPT P10636 8/20 0.56
L3MBTL1 Q9Y468 5/20 0.56
MAPK1 P28482 4/20 0.56
KDM4E B2RXH2 3/20 0.56
NPC1 O15118 2/20 0.56
GLO1 Q04760 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 1/20 0.48
PTPRA P18433 1/20 0.48
PTPRB P23467 1/20 0.48
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.48
RAPGEF4 Q8WZA2 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 5/20 0.48
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
HSP90AA1 P07900 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965822 0.93 THRB (0.65) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL30011390 0.93 THRB (0.65) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL965824 0.93 THRB (0.65) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL8426399 0.93 THRB (0.64) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL7777944 0.93 THRB (0.64) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL11699526 0.92 THRB (0.61) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL4751246 0.87 THRB (0.67) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL30776094 0.83 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL2299642 0.83 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E
SCHEMBL52228 0.83 THRB (0.74) THRBMAPTL3MBTL1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762871-B1 STABILISATION OF PHOTOSENSITIVE MATERIALS SECR DEFENCE (GB) 2003-08-13 EP claimed
US-6379697-B1 LIPOSOMES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND ORTHERN IRELAND (GB) 2002-04-30 US claimed
US-20230014456-A1 ULTRAVIOLET CURABLE EPOXY DIELECTRIC INK RAYTHEON COMPANY 2023-01-19 US disclosed
US-20230017655-A1 ULTRAVIOLET CURABLE EPOXY DIELECTRIC INK RAYTHEON COMPANY 2023-01-19 US disclosed
US-8342241-B2 Delivery of nanodispersions below ground SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2013-01-01 US disclosed
US-20110146974-A1 DELIVERY OF NANODISPERSIONS BELOW GROUND SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-06-23 US disclosed
WO-2004044241-A2 USE OF FISH LARVAE AS A SCREENING MODEL DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung (DE) 2004-05-27 WO disclosed
EP-0762871-B1 STABILISATION OF PHOTOSENSITIVE MATERIALS SECR DEFENCE (GB) 2003-08-13 EP disclosed
US-6379697-B1 LIPOSOMES THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND ORTHERN IRELAND (GB) 2002-04-30 US disclosed
US-4272380-A Solvent front detection method and manufacture ANALYTICAL SYSTEMS, INC. (US) 1981-06-09 US disclosed