Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518227 | 0.86 | MAPT (0.49) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL222789 | 0.73 | — | — | |
| SCHEMBL11808860 | 0.69 | MAPT (0.64) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL9326308 | 0.68 | MAPT (0.67) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL9326305 | 0.68 | MAPT (0.67) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL11811999 | 0.67 | MAPT (0.54) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL15958689 | 0.67 | FURIN (0.48) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL11810867 | 0.66 | MEN1 (0.49) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL11152547 | 0.65 | MAPT (0.39) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL11808112 | 0.65 | ALDH1A1 (0.48) | MAPTSMN1; SMN2MEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296347-A1 | NOVEL DIENE BLOCK FOR USE IN REVERSIBLE CROSSLINKING (HETERO-)DIEL ALDTER POLYMER SYSTEMS | Evonik Degussa GmbH (DE) | 2018-03-21 | — | — | EP | disclosed |