SCHEMBL15958689

SCHEMBL15958689

CCN1CCS/C1=C/C=C/C1=NC(C)(C)CO1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FURIN P09958 1/20 0.48
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
NR2F2 P24468 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
RUNX1 Q01196 1/20 0.47
CBFB Q13951 1/20 0.47
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
INMT O95050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19970840 0.67 MAPT (0.45) MAPTSMN1; SMN2MEN1ALDH1A1KMT2A
SCHEMBL13416790 0.65 FURIN (1.00) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL10035972 0.65 FURIN (1.00) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL12611377 0.65 FURIN (1.00) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL8518227 0.64 MAPT (0.49) MAPTSMN1; SMN2MEN1ALDH1A1KMT2A
Iodide SCHEMBL7704712 0.64 KDM4E (1.00) FURINMAPTSMN1; SMN2MEN1ALDH1A1
Iodide SCHEMBL7704714 0.64 KDM4E (1.00) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL6128334 0.63 FURIN (0.47) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL10066260 0.61 MAPT (0.46) FURINMAPTSMN1; SMN2MEN1ALDH1A1
SCHEMBL222789 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808824-B2 Optical information recording medium, method of recording information and azo metal complex dye FUJIFILM CORPORATION (JP) 2014-08-19 US disclosed