Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28667740 | 0.79 | KDM4E (0.52) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL30415779 | 0.79 | KDM4E (0.52) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9276522 | 0.77 | KCNH2 (0.33) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9276517 | 0.77 | KCNH2 (0.33) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9278575 | 0.76 | HTR2C (0.37) | PDE4A | |
| SCHEMBL29577112 | 0.71 | PDE4A (0.33) | PDE4A | |
| SCHEMBL8486770 | 0.71 | PDE4A (0.33) | PDE4A | |
| SCHEMBL31674081 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1HPGD | |
| SCHEMBL25372896 | 0.67 | CASP7 (0.32) | — | |
| SCHEMBL4865183 | 0.67 | KCNH2 (0.32) | KCNH2KDM4EALDH1A1HPGDCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928892-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF MOXIFLOXACIN HYDROCHLORIDE | MANKIND PHARMA LTD (IN) | 2018-03-21 | — | — | EP | disclosed |