Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357467 | 0.88 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL17509725 | 0.86 | — | — | |
| SCHEMBL19971101 | 0.76 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL17509726 | 0.76 | — | — | |
| SCHEMBL19971135 | 0.74 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL14614393 | 0.71 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL27143635 | 0.69 | SMN1; SMN2 (0.33) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL19044550 | 0.69 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL92633 | 0.69 | SMN1; SMN2 (0.33) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL6411322 | 0.68 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3344678-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | Sika Technology AG (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| CN-107428941-A | Catalyst containing amidino groups | SIKA技术股份公司 | 2017-12-01 | — | — | CN | disclosed |