Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28078125 | 0.86 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2CXCR4 | |
| SCHEMBL2420027 | 0.84 | — | — | |
| SCHEMBL341318 | 0.80 | SMN1; SMN2 (0.34) | SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15541721 | 0.78 | SMN1; SMN2 (0.38) | SIGMAR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL19971135 | 0.77 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL9957528 | 0.77 | HTT (0.40) | SIGMAR1ALDH1A1HTTMAPTHPGD | |
| SCHEMBL9957046 | 0.77 | POLB (0.38) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL19971084 | 0.76 | SIGMAR1 (0.33) | SIGMAR1ALDH1A1HTTCHRM5CHRM3 | |
| SCHEMBL342075 | 0.75 | SMN1; SMN2 (0.40) | SIGMAR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20531089 | 0.75 | GAA (0.35) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261146-B | Polyamines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-01-27 | — | — | CN | claimed |
| CN-103261146-A | Polyamines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | claimed |
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3344678-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | Sika Technology AG (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| CN-107428941-A | Catalyst containing amidino groups | SIKA技术股份公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-103261146-A | Polyamines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | disclosed |