Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971296 | 0.95 | EPHX2 (0.36) | TSHRBBOX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL19971236 | 0.91 | BBOX1 (0.39) | TSHRBBOX1ACACB | |
| SCHEMBL19971297 | 0.85 | BBOX1 (0.43) | TSHRBBOX1 | |
| SCHEMBL19971217 | 0.82 | BBOX1 (0.35) | BBOX1EPHX2 | |
| SCHEMBL19971331 | 0.81 | TSHR (0.34) | TSHRACACB | |
| SCHEMBL19971257 | 0.81 | ZDHHC20 (0.53) | TSHRBBOX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL19971179 | 0.80 | TSHR (0.33) | TSHRBBOX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL19971262 | 0.80 | TSHR (0.37) | TSHR | |
| SCHEMBL19971311 | 0.79 | ZDHHC20 (0.40) | TSHRBBOX1EPHX2ZDHHC20ZDHHC2 | |
| SCHEMBL19971299 | 0.79 | BBOX1 (0.34) | TSHRBBOX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530286-B2 | Sulfobetaine-based protein aggregation inhibitor for use in preventing aggregation of a protein | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2022-12-20 | — | — | US | disclosed |
| US-10995160-B2 | Protein aggregation inhibitor | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2021-05-04 | — | — | US | disclosed |
| US-20200332044-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2020-10-22 | — | — | US | disclosed |
| US-20190161563-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
| US-20180118859-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2018-05-03 | — | — | US | disclosed |
| EP-3296314-A1 | PROTEIN AGGREGATION INHIBITOR | Osaka Organic Chemical Industry Ltd. (JP) | 2018-03-21 | — | — | EP | disclosed |