Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 10/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971352 | 0.85 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL28207563 | 0.84 | IDE (0.42) | IDEHTR6DRD2 | |
| SCHEMBL16626636 | 0.84 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL28857516 | 0.84 | IDE (0.41) | IDEHTR6DRD2 | |
| Hydrochloric Acid SCHEMBL16618813 | 0.83 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16619292 | 0.83 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL19971345 | 0.81 | IDE (0.43) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL16626639 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL17971580 | 0.75 | ALK (0.41) | PDE4APDE4BPDE4CPDE4DIDE | |
| SCHEMBL17971579 | 0.75 | SLC6A2 (0.38) | PDE4APDE4BPDE4CPDE4DIDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |